报告人： Prof. Sang Yup Lee
Korea Advanced Institute of Science & Technology (KAIST)
Sang Yup Lee is Distinguished Professor of Chemical and Biomolecular Engineering, KAIST. He is also Vice President for Research, Director of BioProcess Engineering Research Center, and Director of Bioinformatics Research Center. He served as the Founding Dean of College of Life Science and Bioengineering, and also Dean of KAIST Institutes at KAIST. He is fellow of Korean Academy of Science and Technology, National Academy of Engineering Korea, American Academy of Microbiology, American Institute of Medical and Biological Engineering, World Academy of Sciences, National Academy of Inventors, American Association for the Advancement of Science, American Institute of Chemical Engineers, and Society for Industrial Microbiology and Biotechnology. He is also International Member of both National Academy of Sciences and National Academy of Engineering, USA. He has served as a Chairman of the Global Agenda Council on Emerging Technologies, and also the Global Future Council on Biotechnology at World Economic Forum. He received numerous awards including National Science Medal, National Order of Merit-Red Stripes, Samson Prime Minister’s Prize, Eni Award, James Bailey Award, Marvin Johnson Award, HoAm Prize, and POSCO TJ Park Prize, among others. His research interests include metabolic engineering, industrial biotechnology, synthetic biology, and systems biology. He pioneered systems metabolic engineering.
We are facing great challenges of climate crisis and aging world population. Microorganisms can be employed for the environmentally friendly production of various chemicals and materials including solvents, plastics, drugs and natural products, thus contributing to sustainability and healthier world. However, the efficiencies need to be significantly improved to make the bioprocesses economically competitive. Systems metabolic engineering, which integrates metabolic engineering with the tools and strategies of systems biology, synthetic biology and evolutionary engineering, has become an essential strategy for developing high-performance microbial cell factories. In this lecture, I will describe general strategies and tools of systems metabolic engineering together with several examples strain development for the production of chemicals, fuels, materials, and natural products.